Case histories: breast cancer
Article Outline
Keywords: Anthracycline , Breast cancer , Elderly patients , HER2-positive , Liposomal doxorubicin , Trastuzumab , Triple-negative
No abstract is available. To read the body of this article, please view the PDF online.
References
- . Cancer prevention and screening practices among women at risk for hereditary breast and ovarian cancer after genetic counseling in the community setting . Fam Cancer . 2009;8:277–287
- Triple-negative breast cancer: clinical features and patterns of recurrence . Clin Cancer Res . 2007;13:4429–4434
- . Pattern of metastatic spread in triplenegative breast cancer . Breast Cancer Res Treat . 2009;115:423–428
- Prognosis and adjuvant treatment effects in selected breast cancer subtypes of very young women (<35 years) with operable breast cancer . Ann Oncol . 2010;21:1974–1981
- Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer . J Clin Oncol . 2008;26:1275–1281
- Pathological complete response after preoperative systemic therapy and outcome: relevance of clinical and biologic baseline features . Breast Cancer Res Treat . 2010;124:689–699
- Efficacy of neoadjuvant cisplatin in triple-negative breast cancer . J Clin Oncol . 2010;28:1145–1153
- Neoadjuvant cisplatin and bevacizumab in triple negative breast cancer (TNBC): safety and efficacy . J Clin Oncol . 2009;27(Suppl 15S): abs 551.
- Tailored preoperative treatment of locally advanced triple negative (hormone receptor negative and HER2 negative) breast cancer with epirubicin, cisplatin, and infusional fluorouracil followed by weekly paclitaxel . Cancer Chemother Pharmacol . 2008;62:667–672
- . Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials . Lancet . 2005;365:1687–1717
- Peto R; for the Early Breast Cancer Trialists' Collaborative Group. The worldwide overview: new results for systemic adjuvant therapies. 30th Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, USA, 13-16 December 2007:plenary lecture 1.
- Tissue confirmation of disease recurrence in patients with breast cancer: pooled analysis of two large prospective studies . J Clin Oncol . 2010;28(Suppl 15s): abs 1007.
- First-line chemotherapy for HER-2 negative metastatic breast cancer patients who received anthracyclines as adjuvant treatment . Oncologist . 2007;12:1288–1298
- Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancer . J Clin Oncol . 2010;28:3239–3247
- Efficacy of BSI-201, a poly(ADP-ribose) polymerase-1 (PARP1) inhibitor, in combination with gemcitabine/carboplatin (G/C) in patients with metastatic triplenegative breast cancer (TNBC): results of a randomized phase II trial . J Clin Oncol . 2009;27(Suppl 18s): abs 3.
- . Adjuvant treatment of elderly breast cancer patients . Breast . 2007;16(Suppl 2):S159–S165
- . Effect of age and comorbidity in postmenopausal breast cancer patients aged 55 years and older . JAMA . 2001;285:885–892
- Meta-analysis of breast cancer outcomes in adjuvant trials of aromatase inhibitors versus tamoxifen . J Clin Oncol . 2010;28:509–518
- . Use and outcomes of adjuvant chemotherapy in older women with breast cancer . J Clin Oncol . 2006;24:2750–2756
- . Adjuvant chemotherapy in oestrogenreceptor-poor breast cancer: patient-level meta-analysis of randomised trials . Lancet . 2008;371:29–40
- Adjuvant chemotherapy in older and younger women with lymph node-positive breast cancer . JAMA . 2005;293:1073–1081
- Adjuvant chemotherapy in older women with early-stage breast cancer . N Engl J Med . 2009;360:2055–2065
- Docetaxel with cyclophosphamide is associated with an overall survival benefit compared with doxorubicin and cyclophosphamide: 7-year follow-up of US Oncology Research Trial 9735 . J Clin Oncol . 2009;27:1177–1183
- . Strategies for subtypes - dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011 . Ann Oncol . 2011;22:1736–1747
- . Clinical decision making in breast cancer: TAM and aromatase inhibitors for older patients - a jungle? . Eur J Cancer . 2007;43:2270–2278
- Double-blind, randomized placebo controlled trial of fulvestrant compared with exemestane after prior nonsteroidal aromatase inhibitor therapy in postmenopausal women with hormone receptor-positive, advanced breast cancer: results from EFECT . J Clin Oncol . 2008;26:1664–1670
- Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment . J Clin Oncol . 2002;20:3396–3403
- Management of breast cancer in elderly individuals: recommendations of the International Society of Geriatric Oncology . Lancet Oncol . 2007;8:1101–1115
- . Management of primary and advanced breast cancer in older unfit patients (medical treatment) . Cancer Treat Rev . 2009;35:503–508
- Low-dose oral methotrexate and cyclophosphamide in metastatic breast cancer: antitumor activity and correlation with vascular endothelial growth factor levels . Ann Oncol . 2002;13:73–80
- Multicenter phase II study of capecitabine in paclitaxel-refractory metastatic breast cancer . J Clin Oncol . 1999;17:485–493
- Reduced cardiotoxicity and preserved antitumor efficacy of liposome-encapsulated doxorubicin and cyclophosphamide compared with conventional doxorubicin and cyclophosphamide in a randomized, multicenter trial of metastatic breast cancer . J Clin Oncol . 2001;19:1444–1454
- . Improved anti-tumor response rate with decreased cardiotoxicity of non-pegylated liposomal doxorubicin compared with conventional doxorubicin in first-line treatment of metastatic breast cancer in patients who had received prior adjuvant doxorubicin: results of a retrospective analysis . Anticancer Drugs . 2006;17:587–595
- Liposome-encapsulated doxorubicin compared with conventional doxorubicin in a randomized multicenter trial as first-line therapy of metastatic breast carcinoma . Cancer . 2002;94:25–36
- International Society of Geriatric Oncology (SIOG) clinical practice recommendations for the use of bisphosphonates in elderly patients . Eur J Cancer . 2007;43:852–858
- . New treatment strategies in the management of breast cancer . EJC Suppl . 2011;9(2):22–29
- . Prognosis of women with metastatic breast cancer by HER2 status and trastuzumab treatment: an institutional-based review . J Clin Oncol . 2010;28:92–98
- . Estimation of the epidemiological effect of trastuzumab over 10 years in 5 European countries . J Clin Oncol . 2008;26(Suppl): abs 6589.
- Neoadjuvant chemotherapy with trastuzumab followed by adjuvant trastuzumab versus neoadjuvant chemotherapy alone, in patients with HER2-positive locally advanced breast cancer (the NOAH trial): a randomised controlled superiority trial with a parallel HER2-negative cohort . Lancet . 2010;375:377–384
- Gianni L, Pienkowski T, Im Y-H, et al. Neoadjuvant pertuzumab (P) and trastuzumab (H): antitumor and safety analysis of a randomized phase II study ('NeoSphere'). 33rd Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, USA, 8-12 December 2010:abs S3-2.
- Baselga J, Bradbury I, Eidtmann H, et al. First results of the NeoALTTO trial (BIG 01-06/EGF 106903): a phase III, randomized, open label, neoadjuvant study of lapatinib, trastuzumab, and their combination plus paclitaxel in women with HER2-positive primary breast cancer. 33rd Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, USA, 8-12 December 2010:abs S3-3.
- 2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial . Lancet . 2007;369:29–36
- Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC?T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC?TH) with docetaxel, carboplatin and trastuzumab (TCH) in Her2neu positive early breast cancer patients: BCIRG 006 study . Cancer Res . 2009;69(24 Suppl): abs 62.
- Results of chemotherapy alone, with sequential or concurrent addition of 52 weeks of trastuzumab in the NCCTG N9831 HER2-Positive Adjuvant Breast Cancer Trial . Cancer Res . 2009;69(24 Suppl): abs 80.
- Clinical relevance of HER2 overexpression/amplification in patients with small tumor size and node-negative breast cancer . J Clin Oncol . 2009;27:5693–5699
- High risk of recurrence for patients with breast cancer who have human epidermal growth factor receptor 2-positive, node-negative tumors 1 cm or smaller . J Clin Oncol . 2009;27:5700–5706
- Nonpegylated liposomal doxorubicin (TLC-D99), paclitaxel, and trastuzumab in HER-2-overexpressing breast cancer: a multicenter phase I/II study . Clin Cancer Res . 2009;15:307–314
- A phase I/II trial of non-pegylated liposomal doxorubicin, docetaxel and trastuzumab as first-line treatment in HER-2-positive locally advanced or metastatic breast cancer . Eur J Cancer . 2011 Jun 10; [Epub ahead of print]
- A multicentre Phase II study of non-pegylated liposomal doxorubicin in combination with trastuzumab and docetaxel as first-line therapy in metastatic breast cancer . Breast . 2010;19:333–338
- Phase II clinical trial of liposomal-encapsulated doxorubicin citrate and docetaxel, associated with trastuzumab, as neoadjuvant treatment in stages II and IIIA HER2-overexpressing breast cancer patients. GEICAM 2003-03 study . Ann Oncol . 2010 Jul 5; [Epub ahead of print]
- Randomized phase III trial of weekly compared with every-3-weeks paclitaxel for metastatic breast cancer, with trastuzumab for all HER-2 overexpressors and random assignment to trastuzumab or not in HER-2 nonoverexpressors: final results of Cancer and Leukemia Group B protocol 9840 . J Clin Oncol . 2008;26:1642–1649
- Phase II study of weekly paclitaxel and trastuzumab in anthracycline- and taxane-pretreated patients with HER2-overexpressing metastatic breast cancer . Br J Cancer . 2004;90:36–40
- Randomized phase III study of trastuzumab, paclitaxel, and carboplatin compared with trastuzumab and paclitaxel in women with HER-2-overexpressing metastatic breast cancer . J Clin Oncol . 2006;24:2786–2792
PII: S1359-6349(11)70008-8
doi:10.1016/S1359-6349(11)70008-8
© 2011 Elsevier Ltd. All rights reserved.
